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| MED | Palliative Care Intervention Provides Some Benefits for Patients with Advanced Cancer
Patients with advanced cancer who received a palliative care intervention focused on addressing physical and psychosocial issues and care coordination that was provided at the same time as cancer treatment reported improved quality of life and mood but did not experience a significant change in the number of days in the hospital or the severity of their symptoms compared to patients who received usual care, according to a study in the August 19 issue of JAMA.
(Embargo expired on 18-Aug-2009 at 16:00 ET.)
JAMA, 19-Aug-2009 | 18-Aug-2009
16:00 ET |
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| | —American Medical Association (AMA) | View Article |
| MED | Low-dose Estrogen Shown Safe and Effective for Metastatic Breast Cancer
When estrogen-lowering drugs no longer control metastatic breast cancer, the opposite strategy might work. Raising estrogen levels benefited 30 percent of women whose metastatic breast cancer no longer responded to standard anti-estrogen treatment, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions. (Embargo expired on 18-Aug-2009 at 16:00 ET.)
JAMA, 19-Aug-2009 | 18-Aug-2009
16:00 ET |
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| | —Washington University in St. Louis | View Article |
| MED | Prion Identified as a Novel Early Pancreatic Cancer Biomarker
Mad cow disease is caused by the accumulation of an abnormal protein, the prion, in the brain of an affected patient. Outside of the brain, very little is known about prions. Case Western Reserve University School of Medicine, researchers have, for the first time, identified the prion as a biomarker for pancreatic cancer. (Embargo expired on 17-Aug-2009 at 17:00 ET.)
J. of Clinical Investigation, Sep-2009 | 17-Aug-2009
17:00 ET |
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| | —Case Western Reserve University | View Article |
| MED | Research Points to New Target for Stopping Colon Cancer
New research led by scientists at the University of North Carolina at Chapel Hill School of Medicine have found a drug target that suggests a potent way to kill colon cancers that resist current drugs aimed at blocking a molecule found on the surface of cells. (Embargo expired on 17-Aug-2009 at 17:00 ET.)
J. of Clinical Investigation, 17-Aug-2009 | 17-Aug-2009
17:00 ET |
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| | —University of North Carolina at Chapel Hill School of Medicine | View Article |
| MED | Gene Vital to Brain’s Stem Cells Implicated in Deadly Brain Cancer
Researchers from Columbia University Medical Center’s Herbert Irving Comprehensive Cancer Center have identified a protein that activates brain stem cells to make new neurons – but that may be hijacked later in life to cause brain cancer in humans. The protein called Huwe1 normally functions to eliminate other unnecessary proteins and was found to act as a tumor suppressor in brain cancer. (Embargo expired on 17-Aug-2009 at 12:00 ET.)
Developmental Cell, 18-Aug-2009 | 17-Aug-2009
12:00 ET |
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| | —Columbia University Medical Center | View Article |
| MED | Inherited Risk Factors Increase Odds of Developing Childhood Acute Lymphoblastic Leukemia
Scientists at St. Jude Children’s Research Hospital have identified inherited variations in two genes that account for 37 percent of childhood acute lymphoblastic leukemia (ALL), including a gene that may help predict drug response. (Embargo expired on 16-Aug-2009 at 13:00 ET.)
Nature Genetics, 16-Aug-2009 | 16-Aug-2009
13:00 ET |
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| | —St. Jude Children's Research Hospital | View Article |
| MED | Protein Plays Unexpected Role Protecting Chromosome Tips
A protein specialist that opens the genomic door for DNA repair and gene expression also turns out to be a multi-tasking workhorse that protects the tips of chromosomes and dabbles in a protein-destruction complex, a team lead by researchers at The University of Texas M. D. Anderson Cancer Center reports in the Aug. 13 edition of Molecular Cell.
Molecular Cell, 13-Aug-2009 | 13-Aug-2009
13:00 ET |
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| | —University of Texas M. D. Anderson Cancer Center | View Article |
| MED | Wine May Provide Radioprotective Effect for Breast Cancer Patients
Drinking wine while undergoing radiation treatment for breast carcinoma may reduce the incidence of skin toxicity in breast cancer patients, according to a study in the August issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Radiation Oncology (ASTRO).
International Journal of Radiation Oncology*Biology*Physics, Aug-2009 | 13-Aug-2009
12:45 ET |
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| | —American Society for Radiation Oncology (ASTRO) | View Article |
| MED | New Method Takes Aim at Aggressive Cancer Cells
A multi-institutional team has discovered a chemical that works in mice to kill the rare, aggressive cells within breast cancers that can seed new tumors. These cells, known as cancer stem cells, are thought to enable cancers to spread — and to reemerge after seemingly successful treatment. (Embargo expired on 13-Aug-2009 at 12:00 ET.)
Cell, 13-Aug-2009 | 13-Aug-2009
12:00 ET |
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| | —Whitehead Institute for Biomedical Research | View Article |
| MED | Clinical Trial Targets New Immune Therapy for Kidney Cancer
Researchers at New Jersey’s only NCI-Comprehensive Cancer Center have opened a clinical trial to evaluate whether the standard treatment for a common form of kidney cancer works better by itself or when combined with a certain type of blood cell that comes from a patient’s relative. | 13-Aug-2009
11:35 ET |
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| | —Cancer Institute of New Jersey | View Article |
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